Santiago's Mexican Restaurant
About
This Denver spot draws on the regional depth of Mexican cuisine, moving beyond Tex-Mex to showcase coastal seafood preparations, complex moles, and the bold flavors of Oaxacan and Yucatecan cooking alongside more familiar taqueria fare. The kitchen treats mezcal as more than a novelty, pairing it thoughtfully with dishes that reflect the country's diverse foodways rather than a single regional interpretation. Family recipes and slow-cooked braises suggest an operation built on culinary knowledge rather than trends, where each regional tradition gets its due.
Hours
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Frequently Asked Questions
Santiago's Mexican Restaurant is closed on Sunday.
Santiago's Mexican Restaurant is open on Saturday from 6:00 AM to 8:00 PM.
Monday: 6:00 AM – 8:00 PM, Tuesday: 6:00 AM – 8:00 PM, Wednesday: 6:00 AM – 8:00 PM, Thursday: 6:00 AM – 8:00 PM, Friday: 6:00 AM – 8:00 PM, Saturday: 6:00 AM – 8:00 PM, Sunday: Closed
Santiago's Mexican Restaurant appears to be closed today. Check the full hours schedule on this page.
Santiago's Mexican Restaurant is located at 2505 Federal Boulevard, Denver, CO 80211.
You can reach Santiago's Mexican Restaurant by phone at +1-720-855-8109.
Santiago's Mexican Restaurant does not currently list online reservations. We recommend calling +1-720-855-8109 to inquire about booking a table.
Santiago's Mexican Restaurant serves Mexican Restaurant cuisine.